8 search results - page 1 / 2 » Computing Knock-Out Strategies in Metabolic Networks |
JCB
2008
13 years 4 months ago
2008
Given a metabolic network in terms of its metabolites and reactions, our goal is to efficiently compute the minimal knock out sets of reactions required to block a given behaviour....
BMCBI
2008
13 years 4 months ago
2008
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
BMCBI
2008
13 years 4 months ago
2008
Background: Metabolic networks present a complex interconnected structure, whose understanding is in general a non-trivial task. Several formal approaches have been developed to s...
BCB
2010
12 years 11 months ago
2010
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
CEC
2010
IEEE
12 years 11 months ago
2010
IEEE
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...