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» Defining functional distances over Gene Ontology
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CIBCB
2005
IEEE
13 years 11 months ago
Functional Distances for Genes Based on GO Feature Maps and their Application to Clustering
— With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data, the need for a functiona...
Nora Speer, Holger Fröhlich, Christian Spieth...
ICPR
2008
IEEE
14 years 6 days ago
A fuzzy c-means algorithm using a correlation metrics and gene ontology
A fuzzy c-means algorithm was adapted for analyzing microarray data. The adaptation consisted of initialization of fuzzy centroids using gene ontology information and the use of P...
Mingrui Zhang, Terry M. Therneau, Michael A. McKen...
BMCBI
2004
252views more  BMCBI 2004»
13 years 5 months ago
Applying Support Vector Machines for Gene ontology based gene function prediction
Background: The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to ann...
Arunachalam Vinayagam, Rainer König, Jutta Mo...
ICASSP
2008
IEEE
14 years 7 days ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski