— With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data, the need for a functiona...
A fuzzy c-means algorithm was adapted for analyzing microarray data. The adaptation consisted of initialization of fuzzy centroids using gene ontology information and the use of P...
Mingrui Zhang, Terry M. Therneau, Michael A. McKen...
Background: The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to ann...
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...