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ISMB
1993
13 years 6 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
ISMB
1993
13 years 6 months ago
Probabilistic Structure Calculations: A Three-Dimensional tRNA Structure from Sequence Correlation Data
Algorithmsbasedonprobability theorycanaddressissues of uncertainty directly throughtheir representational frameworkandtheir theoryfor data combination.In this paper, wediscuss the...
Russ B. Altman
RECOMB
2006
Springer
14 years 5 months ago
Detecting the Dependent Evolution of Biosequences
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...
Jeremy Darot, Chen-Hsiang Yeang, David Haussler
BMCBI
2007
106views more  BMCBI 2007»
13 years 5 months ago
Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
Masashi Fujita, Hisaaki Mihara, Susumu Goto, Nobuy...
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
13 years 10 months ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel