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DM
2006
63views more  DM 2006»
13 years 5 months ago
Efficient crossover designs for comparing test treatments with a control treatment
Within a large family of crossover designs this paper characterizes the mathematical structures of A-optimal and A-efficient crossover designs for the purpose of statistical compa...
A. Sadam Hedayat, Min Yang
BIOCOMP
2006
13 years 6 months ago
Structure-Based Design and Analysis of Cytochrome P450 Inhibitors for the Treatment of Prostate Cancer
- Structure-based drug design approach is used to design and analyze cytochrome P450 inhibitors for the treatment of prostate cancer. The structural efficiency of inhibitors is mea...
Muhittin Emre Ozdemir, I. Halil Kavakli, Metin T&u...
AIME
2007
Springer
13 years 11 months ago
Variable Selection for Optimal Decision Making
This paper discusses variable selection for medical decision making; in particular decisions regarding when to provide treatment and which treatment to provide. Current variable se...
Lacey Gunter, Ji Zhu, Susan Murphy
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
BMCBI
2007
113views more  BMCBI 2007»
13 years 5 months ago
Statistical tools for transgene copy number estimation based on real-time PCR
Background: As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughpu...
Joshua S. Yuan, Jason N. Burris, Nathan R. Stewart...