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BMCBI
2010
102views more  BMCBI 2010»
13 years 6 days ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
BMCBI
2010
139views more  BMCBI 2010»
13 years 5 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
13 years 10 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster
BICOB
2010
Springer
13 years 3 months ago
Multiple Kernel Learning for Fold Recognition
Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
Huzefa Rangwala
SDM
2010
SIAM
181views Data Mining» more  SDM 2010»
13 years 6 months ago
A Compression Based Distance Measure for Texture
The analysis of texture is an important subroutine in application areas as diverse as biology, medicine, robotics, and forensic science. While the last three decades have seen ext...
Bilson J. L. Campana, Eamonn J. Keogh