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BMCBI
2006
239views more  BMCBI 2006»
13 years 6 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
JCB
2008
170views more  JCB 2008»
13 years 6 months ago
Efficiently Identifying Max-Gap Clusters in Pairwise Genome Comparison
The spatial clustering of genes across different genomes has been used to study important problems in comparative genomics, from identification of operons to detection of homologo...
Xu Ling, Xin He, Dong Xin, Jiawei Han
BMCBI
2006
127views more  BMCBI 2006»
13 years 6 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2010
115views more  BMCBI 2010»
13 years 6 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
WWW
2010
ACM
14 years 1 months ago
Sampling community structure
We propose a novel method, based on concepts from expander graphs, to sample communities in networks. We show that our sampling method, unlike previous techniques, produces subgra...
Arun S. Maiya, Tanya Y. Berger-Wolf