In this paper we present an approach that evolves the consensus sequence [25] for multiple sequence alignment (MSA) with genetic algorithm (GA). We have developed an encoding schem...
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...