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» Exhaustive prediction of disease susceptibility to coding ba...
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BMCBI
2008
99views more  BMCBI 2008»
13 years 5 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
NAR
2006
100views more  NAR 2006»
13 years 4 months ago
StellaBase: The Nematostella vectensis Genomics Database
ted Talks and Poster Abstracts S1, T1 Title: Evolution of the Mammalian Lamin A Gene Author: Susan N. LoCurto and Dorothy E. Pumo Affiliation: Hofstra University, Department of Bio...
James C. Sullivan, Joseph F. Ryan, James A. Watson...
BMCBI
2007
127views more  BMCBI 2007»
13 years 4 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
IWANN
2009
Springer
13 years 11 months ago
ZARAMIT: A System for the Evolutionary Study of Human Mitochondrial DNA
Abstract. ZARAMIT is an information system capable of fully automated phylogeny reconstruction. Methods have been tailored to mitochondrial DNA sequences, with focus on subproblem ...
Roberto Blanco, Elvira Mayordomo