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DAM
2008
116views more  DAM 2008»
13 years 5 months ago
Expected number of breakpoints after t random reversals in genomes with duplicate genes
In comparative genomics, one wishes to deduce the evolutionary distance between dierent species by studying their genomes. Using gene order information, we seek the number of time...
Niklas Eriksen
RECOMB
2012
Springer
11 years 8 months ago
A Model for Biased Fractionation after Whole Genome Duplication
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
David Sankoff, Chunfang Zheng, Baoyong Wang
CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
13 years 10 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
BMCBI
2005
108views more  BMCBI 2005»
13 years 5 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...