48 search results - page 1 / 10 » Extracting transcription factor binding sites from unaligned... |
BMCBI
2008
13 years 4 months ago
2008
Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hyb...
ISMB
2000
13 years 6 months ago
2000
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
BMCBI
2005
13 years 4 months ago
2005
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
BMCBI
2008
13 years 4 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
BMCBI
2006
13 years 4 months ago
2006
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...