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BIOINFORMATICS
1999
49views more  BIOINFORMATICS 1999»
13 years 5 months ago
Family pairwise search with embedded motif models
William Noble Grundy, Timothy L. Bailey
JCB
1998
92views more  JCB 1998»
13 years 5 months ago
Homology Detection via Family Pairwise Search
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
William Noble Grundy
SAC
2004
ACM
13 years 10 months ago
Guiding motif discovery by iterative pattern refinement
In this paper, we demonstrate that the performance of a motif discovery algorithm can be significantly improved by embedding it into a novel framework that effectively guides the ...
Zhiping Wang, Mehmet M. Dalkilic, Sun Kim
RECOMB
1999
Springer
13 years 9 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy
BMCBI
2006
129views more  BMCBI 2006»
13 years 5 months ago
BIPAD: A web server for modeling bipartite sequence elements
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Chengpeng Bi, Peter K. Rogan