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» Fast detection of common geometric substructure in proteins
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RECOMB
1999
Springer
13 years 9 months ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
BIBE
2007
IEEE
152views Bioinformatics» more  BIBE 2007»
13 years 5 months ago
SBLAST: Structural Basic Local Alignment Searching Tools using Geometric Hashing
While much research has been done on finding similarities between protein sequences, there has not been the same progress on finding similarities between protein structures. Here ...
Tom Milledge, Gaolin Zheng, Tim Mullins, Giri Nara...
BMCBI
2010
163views more  BMCBI 2010»
13 years 5 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
ISDA
2009
IEEE
13 years 11 months ago
Similarity Analysis of Protein Binding Sites: A Generalization of the Maximum Common Subgraph Measure Based on Quasi-Clique Dete
—Protein binding sites are often represented by means of graphs capturing their most important geometrical and physicochemical properties. Searching for structural similarities a...
Imen Boukhris, Zied Elouedi, Thomas Fober, Marco M...
GCB
2008
Springer
174views Biometrics» more  GCB 2008»
13 years 6 months ago
Lightweight Comparison of RNAs based on Exact Sequence-structure Matches
: Specific functions of RNA molecules are often associated with different motifs in the RNA structure. The key feature that forms such an RNA motif is the combination of sequence ...
Steffen Heyne, Sebastian Will, Michael Beckstette,...