Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Recently, some non-coding small RNAs, known as microRNAs (miRNA), have drawn a lot of attention to identify their role in gene regulation and various biological processes. The miRN...
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Background: The recent advancement of microarray technology with lower noise and better affordability makes it possible to determine expression of several thousand genes simultane...
Raja Loganantharaj, Satish Cheepala, John Clifford