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» Finding motifs using random projections
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RECOMB
2001
Springer
14 years 5 months ago
Finding motifs using random projections
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
Jeremy Buhler, Martin Tompa
ALMOB
2006
155views more  ALMOB 2006»
13 years 4 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
BMCBI
2008
99views more  BMCBI 2008»
13 years 4 months ago
NestedMICA as an ab initio protein motif discovery tool
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...
Mutlu Dogruel, Thomas A. Down, Tim J. P. Hubbard
ISAAC
2004
Springer
115views Algorithms» more  ISAAC 2004»
13 years 10 months ago
Randomized Algorithms for Motif Detection
Motivation: Motif detection for DNA sequences has many important applications in biological studies, e.g., locating binding sites and regulatory signals, and designing genetic prob...
Lusheng Wang, Liang Dong, Hui Fan
BMCBI
2007
83views more  BMCBI 2007»
13 years 4 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek