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» Fragment assembly with short reads
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BICOB
2009
Springer
13 years 12 months ago
Assembly of Large Genomes from Paired Short Reads
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Assembly complexity of prokaryotic genomes using short reads
Carl Kingsford, Michael C. Schatz, Mihai Pop
BMCBI
2008
220views more  BMCBI 2008»
13 years 5 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
WABI
2001
Springer
134views Bioinformatics» more  WABI 2001»
13 years 9 months ago
Comparing Assemblies Using Fragments and Mate-Pairs
Using current technology, large consecutive stretches of DNA (such as whole chromosomes) are usually assembled from short fragments obtained by shotgun sequencing, or from fragment...
Daniel H. Huson, Aaron L. Halpern, Zhongwu Lai, Eu...
ISMB
1998
13 years 6 months ago
Sequence Assembly Validation by Multiple Restriction Digest Fragment Coverage Analysis
DNA sequence analysis depends on the accurate assembly of fragment reads for the determination of a consensus sequence. This report examines the possibility of analyzing multiple,...
Eric C. Rouchka, David J. States