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RECOMB
2007
Springer
14 years 5 months ago
Framework for Identifying Common Aberrations in DNA Copy Number Data
High-resolution array comparative genomic hybridization (aCGH) provides exon-level mapping of DNA aberrations in cells or tissues. Such aberrations are central to carcinogenesis an...
Amir Ben-Dor, Doron Lipson, Anya Tsalenko, Mark Re...
BMCBI
2011
12 years 8 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BMCBI
2010
136views more  BMCBI 2010»
13 years 4 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BIBE
2007
IEEE
133views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Denoising of Array-Based DNA Copy Number Data Using The Dual-tree Complex Wavelet Transform
—Array-based comparative genomic hybridization (array CGH) is a highly efficient technique, allowing the simultaneous measurement of genomic DNA copy number at hundreds or thous...
Nha Nguyen, Heng Huang, Soontorn Oraintara, Yuhang...
EVOW
2003
Springer
13 years 10 months ago
Chromosomal Breakpoint Detection in Human Cancer
Chromosomal aberrations are differences in DNA sequence copy number of chromosome regions 3 . These differences may be crucial genetic events in the development and progression o...
Kees Jong, Elena Marchiori, Aad van der Vaart, Bau...