Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
The queueing Petri net (QPN) paradigm provides a number of benefits over conventional modeling paradigms such as queueing networks and generalized stochastic Petri nets. Using qu...
Biomodel engineering is the science of designing, constructing and analyzing computational models of biological systems. It forms a systematic and powerful extension of earlier mat...
Rainer Breitling, Robin Donaldson, David R. Gilber...
Abstract—Service requests are the origin of every service provisioning process and therefore the entities to be considered first. Similar to Physics and Engineering Sciences, ser...