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» Functional discrimination of membrane proteins using machine...
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BMCBI
2008
100views more  BMCBI 2008»
13 years 4 months ago
High-precision high-coverage functional inference from integrated data sources
Background: Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of k...
Bolan Linghu, Evan S. Snitkin, Dustin T. Holloway,...
BMCBI
2007
129views more  BMCBI 2007»
13 years 4 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2006
150views more  BMCBI 2006»
13 years 4 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils
ISMB
1998
13 years 6 months ago
Identification of Divergent Functions in Homologous Proteins by Induction over Conserved Modules
Homologousproteins do not necessarily exhibit identical biochemicalfunction. Despitethis fact, local or global sequence similarity is widely used as an indication of functional id...
Imran Shah, Lawrence Hunter
BIOCOMP
2006
13 years 6 months ago
Insight of the Signal Motif of GPI-(like)-anchored Proteins by using SVM
- Many proteins contain a signal sequence at their COOH-terminus recognized by glycosylphosphatidylinositol (GPI) anchor and attached on the membrane. Experimental result suggests ...
Wei Cao, Kazuya Sumikoshi, Tohru Terada, Shugo Nak...