In the present article, we introduce a new method for identification of metabolic pathways in constraint based models that consider enzyme and substrate concentrations. It genera...
C. A. Murthy, Mouli Das, Rajat K. De, Subhasis Muk...
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
—Metabolic pathways are crucial to our understanding of biology. The speed at which new organisms are being sequenced is outstripping our ability to experimentally determine thei...
Luca Pireddu, Brett Poulin, Duane Szafron, Paul Lu...
Metabolism can be regarded as a network of biochemical reactions, connected via their substrates and products. A metabolic pathway is thus a coordinated series of reactions, and i...
Given concentrations of metabolites over a sequence of time steps, the metabolic pathway prediction problem seeks a set of reactions and rate constants for them that could yield t...