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» GENOME: a rapid coalescent-based whole genome simulator
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BMCBI
2008
123views more  BMCBI 2008»
13 years 4 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...
TCS
2008
13 years 4 months ago
GemCell: A generic platform for modeling multi-cellular biological systems
The mass and complexity of biological information requires computer-aided simulation and analysis to help scientists achieve understanding and guide experimentation. Although livi...
Hila Amir-Kroll, Avital Sadot, Irun R. Cohen, Davi...
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
13 years 10 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
JCB
2006
125views more  JCB 2006»
13 years 4 months ago
Hypothesis Generation in Signaling Networks
Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulati...
Derek A. Ruths, Luay Nakhleh, M. Sriram Iyengar, S...