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» GOtcha: a new method for prediction of protein function asse...
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BMCBI
2008
130views more  BMCBI 2008»
13 years 4 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2007
131views more  BMCBI 2007»
13 years 4 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
13 years 11 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
BMCBI
2010
118views more  BMCBI 2010»
13 years 4 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...