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» Genome Rearrangement: A Planning Approach
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JCB
2007
146views more  JCB 2007»
13 years 5 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
BMCBI
2007
154views more  BMCBI 2007»
13 years 5 months ago
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Amit U. Sinha, Jaroslaw Meller
RECOMB
2004
Springer
14 years 5 months ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh
COCOON
2005
Springer
13 years 10 months ago
Genome Rearrangements with Partially Ordered Chromosomes
Genomic maps often do not specify the order within some groups of two or more markers. The synthesis of a master map from several sources introduces additional order ambiguity due ...
Chunfang Zheng, David Sankoff
WABI
2009
Springer
181views Bioinformatics» more  WABI 2009»
13 years 12 months ago
Decoding Synteny Blocks and Large-Scale Duplications in Mammalian and Plant Genomes
Abstract. The existing synteny block reconstruction algorithms use anchors (e.g., orthologous genes) shared over all genomes to construct the synteny blocks for multiple genomes. T...
Qian Peng, Max A. Alekseyev, Glenn Tesler, Pavel A...