Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Abstract. The objective function of the genome rearrangement problems allows the integration of other genome-level problems so that they may be solved simultaneously. Three example...
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Given two genomes with duplicate genes, Zero Exemplar Distance is the problem of deciding whether the two genomes can be reduced to the same genome without duplicate genes by delet...