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» Genome-wide prediction of transcriptional regulatory element...
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BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
BMCBI
2007
247views more  BMCBI 2007»
13 years 9 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2007
106views more  BMCBI 2007»
13 years 9 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
FUZZIEEE
2007
IEEE
14 years 3 months ago
Mining and Predicting CpG islands
— A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
Christopher Previti, Oscar Harari, Coral del Val
BMCBI
2008
169views more  BMCBI 2008»
13 years 9 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...