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GECCO
2000
Springer
123views Optimization» more  GECCO 2000»
13 years 8 months ago
Genomic computing: explanatory modelling for functional genomics
Many newly discovered genes are of unknown function. DNA microarrays are a method for determining the expression levels of all genes in an organism for which a complete genome seq...
Richard J. Gilbert, Jem J. Rowland, Douglas B. Kel...
JCB
2008
144views more  JCB 2008»
13 years 4 months ago
Multi-Break Rearrangements and Breakpoint Re-Uses: From Circular to Linear Genomes
Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2-break rearrangements represent standard reversals, fusions...
Max A. Alekseyev
RECOMB
2012
Springer
11 years 7 months ago
A Model for Biased Fractionation after Whole Genome Duplication
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
David Sankoff, Chunfang Zheng, Baoyong Wang
NAR
2011
208views Computer Vision» more  NAR 2011»
12 years 7 months ago
Tomato Functional Genomics Database: a comprehensive resource and analysis package for tomato functional genomics
Tomato Functional Genomics Database (TFGD) provides a comprehensive resource to store, query, mine, analyze, visualize and integrate large-scale tomato functional genomics data se...
Zhangjun Fei, Je-Gun Joung, Xuemei Tang, Yi Zheng,...
BMCBI
2006
120views more  BMCBI 2006»
13 years 4 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu