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BMCBI
2010
142views more  BMCBI 2010»
13 years 5 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
JMLR
2010
136views more  JMLR 2010»
12 years 11 months ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender
RECOMB
2006
Springer
14 years 5 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...