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BMCBI
2010
142views more  BMCBI 2010»
13 years 5 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
JMLR
2010
136views more  JMLR 2010»
13 years 2 days ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender
RECOMB
2006
Springer
14 years 5 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 11 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...