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BMCBI
2004
90views more  BMCBI 2004»
13 years 4 months ago
Haplotype frequency estimation error analysis in the presence of missing genotype data
Background: Increasingly researchers are turning to the use of haplotype analysis as a tool in population studies, the investigation of linkage disequilibrium, and candidate gene ...
Enda D. Kelly, Fabian Sievers, Ross McManus
RECOMB
2004
Springer
14 years 5 months ago
Perfect phylogeny and haplotype assignment
This paper is concerned with the reconstruction of perfect phylogenies from binary character data with missing values, and related problems of inferring complete haplotypes from h...
Eran Halperin, Richard M. Karp
JCB
2006
140views more  JCB 2006»
13 years 4 months ago
HAPLOFREQ-Estimating Haplotype Frequencies Efficiently
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Eran Halperin, Elad Hazan
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick
BMCBI
2008
138views more  BMCBI 2008»
13 years 4 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...