Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods ...
We derive a branch-and-bound algorithm to find an optimal inversion median of three signed permutations. The algorithm prunes to manageable size an extremely large search tree usi...
In the median problem, we are given a distance or dissimilarity measure d, three genomes G1, G2, and G3, and we want to find a genome G (a median) such that the sum 3 i=1 d(G, Gi...
Enno Ohlebusch, Mohamed Ibrahim Abouelhoda, Kathri...