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BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
RECOMB
2007
Springer
14 years 5 months ago
Improving Inversion Median Computation Using Commuting Reversals and Cycle Information
In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods ...
William Arndt, Jijun Tang
WABI
2001
Springer
112views Bioinformatics» more  WABI 2001»
13 years 9 months ago
Finding an Optimal Inversion Median: Experimental Results
We derive a branch-and-bound algorithm to find an optimal inversion median of three signed permutations. The algorithm prunes to manageable size an extremely large search tree usi...
Adam C. Siepel, Bernard M. E. Moret
JDA
2007
156views more  JDA 2007»
13 years 4 months ago
A linear time algorithm for the inversion median problem in circular bacterial genomes
In the median problem, we are given a distance or dissimilarity measure d, three genomes G1, G2, and G3, and we want to find a genome G (a median) such that the sum 3 i=1 d(G, Gi...
Enno Ohlebusch, Mohamed Ibrahim Abouelhoda, Kathri...
HEURISTICS
2002
88views more  HEURISTICS 2002»
13 years 4 months ago
The Parallel Variable Neighborhood Search for the p-Median Problem
Félix García-López, Bel&eacut...