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» Hierarchical multi-label prediction of gene function
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ICPR
2008
IEEE
13 years 11 months ago
Gene function prediction using protein domain probability and hierarchical Gene Ontology information
The Gene Ontology (GO) is a controlled vocabulary of terms to describe protein functions. It also includes a hierarchical description of the relationships among the terms in the f...
Jaehee Jung, Michael R. Thon
JMLR
2010
133views more  JMLR 2010»
12 years 11 months ago
Hierarchical Cost-Sensitive Algorithms for Genome-Wide Gene Function Prediction
In this work we propose new ensemble methods for the hierarchical classification of gene functions. Our methods exploit the hierarchical relationships between the classes in diffe...
Nicolò Cesa-Bianchi, Giorgio Valentini
BMCBI
2010
109views more  BMCBI 2010»
13 years 5 months ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BIOINFORMATICS
2006
67views more  BIOINFORMATICS 2006»
13 years 5 months ago
Hierarchical multi-label prediction of gene function
Zafer Barutçuoglu, Robert E. Schapire, Olga...