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» Identification and Evaluation of Functional Modules in Gene ...
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BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express
Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Chih-Hung Jen, Tsun-Po Yang, Chien-Yi Tung, Shu-Ha...
BMCBI
2007
157views more  BMCBI 2007»
13 years 5 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
BCB
2010
127views Bioinformatics» more  BCB 2010»
13 years 13 days ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BMCBI
2008
141views more  BMCBI 2008»
13 years 5 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
BMCBI
2010
160views more  BMCBI 2010»
13 years 5 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...