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BMCBI
2010
115views more  BMCBI 2010»
13 years 4 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BMCBI
2010
149views more  BMCBI 2010»
13 years 4 months ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët
BMCBI
2010
171views more  BMCBI 2010»
13 years 4 months ago
PyMix - The Python mixture package - a tool for clustering of heterogeneous biological data
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...
ISBRA
2009
Springer
13 years 11 months ago
Integrating Multiple-Platform Expression Data through Gene Set Features
Abstract. We demonstrate a set-level approach to the integration of multiple platform gene expression data for predictive classification and show its utility for boosting classi...
Matej Holec, Filip Zelezný, Jirí Kl&...
BMCBI
2010
124views more  BMCBI 2010»
13 years 4 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...