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» Improved Recombination Lower Bounds for Haplotype Data
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RECOMB
2005
Springer
14 years 5 months ago
Improved Recombination Lower Bounds for Haplotype Data
Recombination is an important evolutionary mechanism responsible for the genetic diversity in humans and other organisms. Recently, there has been extensive research on understandi...
Vineet Bafna, Vikas Bansal
WABI
2007
Springer
110views Bioinformatics» more  WABI 2007»
13 years 11 months ago
Haplotype Inference Via Hierarchical Genotype Parsing
The within-species genetic variation due to recombinations leads to a mosaic-like structure of DNA. This structure can be modeled, e.g. by parsing sample sequences of current DNA w...
Pasi Rastas, Esko Ukkonen
CONSTRAINTS
2008
78views more  CONSTRAINTS 2008»
13 years 4 months ago
Boosting Haplotype Inference with Local Search
Abstract. A very challenging problem in the genetics domain is to infer haplotypes from genotypes. This process is expected to identify genes affecting health, disease and response...
Inês Lynce, João Marques-Silva, Steve...
CPAIOR
2008
Springer
13 years 6 months ago
Efficient Haplotype Inference with Combined CP and OR Techniques
Abstract. Haplotype inference has relevant biological applications, and represents a challenging computational problem. Among others, pure parsimony provides a viable modeling appr...
Ana Graça, João Marques-Silva, In&ec...
BMCBI
2010
106views more  BMCBI 2010»
13 years 5 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li