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CDC
2008
IEEE
115views Control Systems» more  CDC 2008»
13 years 11 months ago
Design and performance of in vitro transcription rate regulatory circuits
— This paper proposes a synthetic in vitro circuit that aims at regulating the rate of RNA transcription through positive feedback interactions. This design is dual to a previous...
Elisa Franco, Richard M. Murray
UMC
2000
13 years 8 months ago
In-vitro Transcriptional Circuits
The structural similarity of neural networks and genetic regulatory networks to digital circuits, and hence to each other, was noted from the very beginning of their study [1, 2]....
Erik Winfree
BMCBI
2010
240views more  BMCBI 2010»
13 years 4 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
BMCBI
2006
169views more  BMCBI 2006»
13 years 4 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
CCE
2005
13 years 4 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis