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BMCBI
2005
113views more  BMCBI 2005»
13 years 5 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BIBM
2008
IEEE
107views Bioinformatics» more  BIBM 2008»
14 years 3 days ago
A Functional Network of Yeast Genes Using Gene Ontology Information
In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
CSB
2005
IEEE
168views Bioinformatics» more  CSB 2005»
13 years 11 months ago
cis-Regulatory Element Prediction in Mammalian Genomes
The identification of cis-regulatory elements and modules is an important step in understanding the regulation of genes. We have developed a pipeline capable of running multiple m...
Asim S. Siddiqui, Gordon Robertson, Misha Bilenky,...
CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
13 years 11 months ago
Biological Pathway Prediction from Multiple Data Sources Using Iterative Bayesian Updating
There is a diversity of functional genomics data, such as gene expression data from microarray experiments, phenotypic data from gene deletion experiments, protein-protein interac...
Corey Powell, Joshua M. Stuart
CSB
2004
IEEE
106views Bioinformatics» more  CSB 2004»
13 years 9 months ago
Positive Sample Only Learning (PSOL) for Predicting RNA Genes in E. coli
RNA genes lack most of the signals used for protein gene identification. A major shortcoming of previous discriminative methods to distinguish functional RNA (fRNA) genes from oth...
Richard F. Meraz, Xiaofeng He, Chris H. Q. Ding, S...