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» Inverse Sequence Alignment from Partial Examples
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WABI
2007
Springer
123views Bioinformatics» more  WABI 2007»
9 years 10 months ago
Inverse Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Eagu Kim, John D. Kececioglu
TCBB
2008
120views more  TCBB 2008»
9 years 3 months ago
Learning Scoring Schemes for Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of scoring scheme is critical. Even small changes in gap penalties, for example, can yield radically different alignments. A rigorous...
Eagu Kim, John D. Kececioglu
RECOMB
2006
Springer
10 years 4 months ago
Simple and Fast Inverse Alignment
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...
John D. Kececioglu, Eagu Kim
IDA
2007
Springer
9 years 10 months ago
Learning to Align: A Statistical Approach
We present a new machine learning approach to the inverse parametric sequence alignment problem: given as training examples a set of correct pairwise global alignments, find the p...
Elisa Ricci, Tijl De Bie, Nello Cristianini
CPM
1993
Springer
154views Combinatorics» more  CPM 1993»
9 years 8 months ago
On Suboptimal Alignments of Biological Sequences
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re ect the correct biolog...
Dalit Naor, Douglas L. Brutlag
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