8 search results - page 1 / 2 » JISTIC: Identification of Significant Targets in Cancer |
BMCBI
2010
13 years 4 months ago
2010
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
RECOMB
2010
Springer
13 years 6 months ago
2010
Springer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
BIBM
2009
IEEE
13 years 10 months ago
2009
IEEE
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
BMCBI
2005
13 years 4 months ago
2005
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
BMCBI
2004
13 years 4 months ago
2004
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....