Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...