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» MDGA: motif discovery using a genetic algorithm
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BMCBI
2006
108views more  BMCBI 2006»
13 years 6 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
KES
2005
Springer
13 years 11 months ago
Generalized Composite Motif Discovery
This paper discusses a general algorithm for the discovery of motif combinations. From a large number of input motifs, discovered by any single motif discovery tool, our algorithm ...
Geir Kjetil Sandve, Finn Drabløs
APBC
2004
163views Bioinformatics» more  APBC 2004»
13 years 7 months ago
A Combined Model and a Varied Gibbs Sampling Algorithm Used for Motif Discovery
The conserved sequences in gene regulatory regions dominate gene regulation. Discovering these sequences and their functions is important in post genome era. A novel model is cons...
Xiaoming Wu, Bo Wang, Changxin Song, Jingzhi Cheng
BMCBI
2007
145views more  BMCBI 2007»
13 years 6 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
RECOMB
2003
Springer
14 years 6 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...