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BMCBI
2010
115views more  BMCBI 2010»
13 years 5 months ago
Machine learning methods for metabolic pathway prediction
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
Joseph M. Dale, Liviu Popescu, Peter D. Karp
APBC
2003
141views Bioinformatics» more  APBC 2003»
13 years 7 months ago
Comparison of Metabolic Pathways using Constraint Graph Drawing
Databases contain a large amount of data about metabolic pathways, in particular about similar pathways in different species. Biologists are familiar with visual representations ...
Falk Schreiber
BMCBI
2010
156views more  BMCBI 2010»
13 years 5 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
RECOMB
1999
Springer
13 years 10 months ago
Evolution of metabolisms: a new method for the comparison of metabolic pathways
The abundance of information provided by completely sequenced genomes de nes a starting point for new insights in the multilevel organization of organisms and their evolution. At ...
Christian V. Forst, Klaus Schulten
NAR
2006
177views more  NAR 2006»
13 years 5 months ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...