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RECOMB
1999
Springer
13 years 9 months ago
Evolution of metabolisms: a new method for the comparison of metabolic pathways
The abundance of information provided by completely sequenced genomes de nes a starting point for new insights in the multilevel organization of organisms and their evolution. At ...
Christian V. Forst, Klaus Schulten
BMCBI
2010
156views more  BMCBI 2010»
13 years 5 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
13 years 11 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
BMCBI
2006
50views more  BMCBI 2006»
13 years 4 months ago
Metabolic pathways variability and sequence/networks comparisons
Kyaw Tun, Pawan K. Dhar, Maria Concetta Palumbo, A...
BMCBI
2010
115views more  BMCBI 2010»
13 years 5 months ago
Machine learning methods for metabolic pathway prediction
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
Joseph M. Dale, Liviu Popescu, Peter D. Karp