47 search results - page 1 / 10 » Methods for Designing Reliable Probe Arrays |
BIBE
2010
IEEE
13 years 5 months ago
2010
IEEE
Recent advances in biosensing technologies have led to applications of biosensor probe arrays for rapid identification of biological agents such as drugs, gene expressions, protein...
TCBB
2011
12 years 11 months ago
2011
— Probe defects are a major source of noise in gene expression studies. While existing approaches detect noisy probes based on external information such as genomic alignments, we...
BMCBI
2008
13 years 4 months ago
2008
Background: Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mi...
BMCBI
2008
13 years 4 months ago
2008
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
BMCBI
2010
13 years 4 months ago
2010
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...