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» Multiple Genome Alignment by Clustering Pairwise Matches
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ECCB
2008
IEEE
13 years 11 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial
BMCBI
2010
155views more  BMCBI 2010»
13 years 2 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2004
106views more  BMCBI 2004»
13 years 4 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
APBC
2004
108views Bioinformatics» more  APBC 2004»
13 years 6 months ago
Ladderlike Stepping and Interval Jumping Searching Algorithms for DNA Sequences
In this study we have designed a novel algorithm for searching common segments in multiple DNA sequences. To improve efficiency in pattern searching, combination of hashing encodi...
Tun-Wen Pai, Margaret Dah-Tsyr Chang, Jia-Han Chu,...
BMCBI
2006
144views more  BMCBI 2006»
13 years 4 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...