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» Non-additivity in protein-DNA binding
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BMCBI
2002
101views more  BMCBI 2002»
13 years 5 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
CSB
2003
IEEE
153views Bioinformatics» more  CSB 2003»
13 years 10 months ago
Combining Microarrays and Biological Knowledge for Estimating Gene Networks via Bayesian Networks
We propose a statistical method for estimating a gene network based on Bayesian networks from microarray gene expression data together with biological knowledge including protein-...
Seiya Imoto, Tomoyuki Higuchi, Takao Goto, Kousuke...
RECOMB
2005
Springer
14 years 5 months ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola