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» Occam's Razor Applied to Network Topology Inference
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ALIFE
2008
13 years 4 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
BMCBI
2008
129views more  BMCBI 2008»
13 years 5 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BIOCOMP
2010
13 years 1 months ago
A Network-based Approach to Classify Disease Stages of Prostate Cancer Using Quantitative Network Measures
Abstract-- This study deals with investigating the classification performance of information-theoretic measures when applied to complex biological networks. In particular, our aim ...
Laurin A. J. Mueller, Karl G. Kugler, Andreas Dand...
BMCBI
2008
116views more  BMCBI 2008»
13 years 5 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
RECOMB
2008
Springer
14 years 5 months ago
Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer
Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
Cuong Than, Guohua Jin, Luay Nakhleh