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» On Recovering Syntenic Blocks from Comparative Maps
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COCOA
2008
Springer
13 years 6 months ago
On Recovering Syntenic Blocks from Comparative Maps
A genomic map is represented by a sequence of gene markers, and a gene marker can appear in several different genomic maps, in either positive or negative form. A strip (syntenic b...
Zhixiang Chen, Bin Fu, Minghui Jiang, Binhai Zhu
WABI
2007
Springer
122views Bioinformatics» more  WABI 2007»
13 years 11 months ago
Algorithms for the Extraction of Synteny Blocks from Comparative Maps
In comparing genomic maps, it is often difficult to distinguish mapping errors and incorrectly resolved paralogies from genuine rearrangements of the genomes. A solution to this ...
Vicky Choi, Chunfang Zheng, Qian Zhu, David Sankof...
ALMOB
2008
160views more  ALMOB 2008»
13 years 5 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
HICSS
2003
IEEE
166views Biometrics» more  HICSS 2003»
13 years 10 months ago
Comparative Genome Annotation for Mapping, Prediction and Discovery of Genes
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
Claudia Kappen, J. Michael Salbaum
BMCBI
2011
12 years 12 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...