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» On Timed Models of Gene Networks
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CMSB
2006
Springer
13 years 9 months ago
Incorporating Time Delays into the Logical Analysis of Gene Regulatory Networks
Based on the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach that uses timed automata. It yields a refined quali...
Heike Siebert, Alexander Bockmayr
BMCBI
2010
110views more  BMCBI 2010»
13 years 5 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
GECCO
2004
Springer
132views Optimization» more  GECCO 2004»
13 years 10 months ago
Optimizing Topology and Parameters of Gene Regulatory Network Models from Time-Series Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. Different approaches to infer the dependencies of gene r...
Christian Spieth, Felix Streichert, Nora Speer, An...
ISBRA
2010
Springer
13 years 3 months ago
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Data
A popular model for gene regulatory networks is the Boolean network model. In this paper, we propose an algorithm to perform an analysis of gene regulatory interactions using the B...
Carlos H. A. Higa, Vitor H. P. Louzada, Ronaldo Fu...
BIOCOMP
2008
13 years 6 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...