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» On the Effectiveness of Constraints Sets in Clustering Genes
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BIBE
2007
IEEE
151views Bioinformatics» more  BIBE 2007»
13 years 6 months ago
On the Effectiveness of Constraints Sets in Clustering Genes
—In this paper, we have modified a constrained clustering algorithm to perform exploratory analysis on gene expression data using prior knowledge presented in the form of constr...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
BMCBI
2010
115views more  BMCBI 2010»
13 years 4 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
TCSB
2008
13 years 4 months ago
Clustering Time-Series Gene Expression Data with Unequal Time Intervals
Clustering gene expression data given in terms of time-series is a challenging problem that imposes its own particular constraints, namely exchanging two or more time points is not...
Luis Rueda, Ataul Bari, Alioune Ngom
RECOMB
2008
Springer
14 years 4 months ago
Computation of Median Gene Clusters
Whole genome comparison based on gene order has become a popular approach in comparative genomics. An important task in this field is the detection of gene clusters, i.e. sets of g...
Sebastian Böcker, Katharina Jahn, Julia Mixta...
CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Gene Teams with Relaxed Proximity Constraint
Functionally related genes co-evolve, probably due to the strong selection pressure in evolution. Thus we expect that they are present in multiple genomes. Physical proximity amon...
Sun Kim, Jeong-Hyeon Choi, Jiong Yang