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JMLR
2010
136views more  JMLR 2010»
12 years 11 months ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender
BMCBI
2008
95views more  BMCBI 2008»
13 years 4 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
WOB
2008
101views Bioinformatics» more  WOB 2008»
13 years 6 months ago
Top-Down Hierarchical Ensembles of Classifiers for Predicting G-Protein-Coupled-Receptor Functions
Abstract. Despite the recent advances in Molecular Biology, the function of a large amount of proteins is still unknown. An approach that can be used in the prediction of a protein...
Eduardo P. Costa, Ana Carolina Lorena, André...
BMCBI
2010
102views more  BMCBI 2010»
12 years 12 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
RECOMB
2003
Springer
14 years 5 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun