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BMCBI
2007
131views more  BMCBI 2007»
13 years 4 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
BIBE
2006
IEEE
184views Bioinformatics» more  BIBE 2006»
13 years 11 months ago
A Language Modeling Text Mining Approach to the Annotation of Protein Community
This paper discusses an ontology based language modeling text mining approach to the annotation of protein community. Communities appear to play an important role in the functional...
Xiaodan Zhang, Daniel Duanqing Wu, Xiaohua Zhou, X...
BMCBI
2005
253views more  BMCBI 2005»
13 years 4 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
NAR
2007
90views more  NAR 2007»
13 years 4 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
BMCBI
2005
136views more  BMCBI 2005»
13 years 4 months ago
Automatic detection of false annotations via binary property clustering
Background: Computational protein annotation methods occasionally introduce errors. Falsepositive (FP) errors are annotations that are mistakenly associated with a protein. Such f...
Noam Kaplan, Michal Linial